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Functional consequences of DECTIN-1 early stop codon polymorphism Y238X in rheumatoid arthritis
INTRODUCTION: Dectin-1, a pattern recognition receptor expressed by the innate immune system, is known to be a major receptor inducing Th17-type adaptive immune responses that have been demonstrated to mediate autoimmunity. In this study, dectin-1 mRNA and protein expression, as well as the recently...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875660/ https://www.ncbi.nlm.nih.gov/pubmed/20158887 http://dx.doi.org/10.1186/ar2933 |