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Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursors

INTRODUCTION: The interaction between the immune and skeletal systems is evidenced by the bone loss observed in autoimmune diseases such as rheumatoid arthritis. In this paper we describe a new mechanism by which the immune cytokine IL-17A directly affects osteoclastogenesis. METHODS: Human CD14(+ )...

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Detalles Bibliográficos
Autores principales: Adamopoulos, Iannis E, Chao, Cheng-chi, Geissler, Richard, Laface, Drake, Blumenschein, Wendy, Iwakura, Yoichiro, McClanahan, Terrill, Bowman, Edward P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875663/
https://www.ncbi.nlm.nih.gov/pubmed/20167120
http://dx.doi.org/10.1186/ar2936