Inhibitory Effects of Anti-VEGF Antibody on the Growth and Angiogenesis of Estrogen-induced Pituitary Prolactinoma in Fischer 344 Rats: Animal Model of VEGF-targeted Therapy for Human Endocrine Tumors

Estrogen-induced pituitary prolactin-producing tumors (PRLoma) in F344 rats express a high level of vascular endothelial growth factor (VEGF) associated with marked angiogenesis and angiectasis. To investigate whether tumor development in E2-induced PRLoma is inhibited by anti-VEGF monoclonal antibo...

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Detalles Bibliográficos
Autores principales: Miyajima, Katsuhiro, Takekoshi, Susumu, Itoh, Johbu, Kakimoto, Kochi, Miyakoshi, Takashi, Osamura, Robert Yoshiyuki
Formato: Texto
Lenguaje:English
Publicado: Japan Society of Histochemistry and Cytochemistry 2010
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875861/
https://www.ncbi.nlm.nih.gov/pubmed/20514290
http://dx.doi.org/10.1267/ahc.09034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875861/
https://www.ncbi.nlm.nih.gov/pubmed/20514290
http://dx.doi.org/10.1267/ahc.09034

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