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Inhibitory Effects of Anti-VEGF Antibody on the Growth and Angiogenesis of Estrogen-induced Pituitary Prolactinoma in Fischer 344 Rats: Animal Model of VEGF-targeted Therapy for Human Endocrine Tumors

Estrogen-induced pituitary prolactin-producing tumors (PRLoma) in F344 rats express a high level of vascular endothelial growth factor (VEGF) associated with marked angiogenesis and angiectasis. To investigate whether tumor development in E2-induced PRLoma is inhibited by anti-VEGF monoclonal antibo...

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Detalles Bibliográficos
Autores principales:	Miyajima, Katsuhiro, Takekoshi, Susumu, Itoh, Johbu, Kakimoto, Kochi, Miyakoshi, Takashi, Osamura, Robert Yoshiyuki
Formato:	Texto
Lenguaje:	English
Publicado:	Japan Society of Histochemistry and Cytochemistry 2010
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875861/ https://www.ncbi.nlm.nih.gov/pubmed/20514290 http://dx.doi.org/10.1267/ahc.09034

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