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Doxorubicin and etoposide sensitize small cell lung carcinoma cells expressing caspase-8 to TRAIL

BACKGROUND: TRAIL is considered as a promising anti-cancer agent, because of its ability to induce apoptosis in cancer but not in most normal cells. However, growing evidence exist that many cancer cells are resistant to its apoptotic effects. SCLC is a typical example of tumor entity where TRAIL mo...

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Detalles Bibliográficos
Autores principales: Vaculova, Alena, Kaminskyy, Vitaliy, Jalalvand, Elham, Surova, Olga, Zhivotovsky, Boris
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876059/
https://www.ncbi.nlm.nih.gov/pubmed/20416058
http://dx.doi.org/10.1186/1476-4598-9-87