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Structural fragment clustering reveals novel structural and functional motifs in α-helical transmembrane proteins

BACKGROUND: A large proportion of an organism's genome encodes for membrane proteins. Membrane proteins are important for many cellular processes, and several diseases can be linked to mutations in them. With the tremendous growth of sequence data, there is an increasing need to reliably identi...

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Detalles Bibliográficos
Autores principales: Marsico, Annalisa, Henschel, Andreas, Winter, Christof, Tuukkanen, Anne, Vassilev, Boris, Scheubert, Kerstin, Schroeder, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876129/
https://www.ncbi.nlm.nih.gov/pubmed/20420672
http://dx.doi.org/10.1186/1471-2105-11-204