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From 'omics' to complex disease: a systems biology approach to gene-environment interactions in cancer

BACKGROUND: Cancer is a complex disease that involves a sequence of gene-environment interactions in a progressive process that cannot occur without dysfunction in multiple systems, including DNA repair, apoptotic and immune functions. Epigenetic mechanisms, responding to numerous internal and exter...

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Detalles Bibliográficos
Autor principal: Knox, Sarah S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876152/
https://www.ncbi.nlm.nih.gov/pubmed/20420667
http://dx.doi.org/10.1186/1475-2867-10-11