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Developmental iodine deficiency and hypothyroidism impair neural development in rat hippocampus: involvement of doublecortin and NCAM-180

BACKGROUND: Developmental iodine deficiency results in inadequate thyroid hormone (TH), which damages the hippocampus. Here, we explored the roles of hippocampal doublecortin and neural cell adhesion molecule (NCAM)-180 in developmental iodine deficiency and hypothyroidism. METHODS: Two developmenta...

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Detalles Bibliográficos
Autores principales: Gong, Jian, Liu, Wanyang, Dong, Jing, Wang, Yi, Xu, Hongde, Wei, Wei, Zhong, Jiapeng, Xi, Qi, Chen, Jie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876162/
https://www.ncbi.nlm.nih.gov/pubmed/20412599
http://dx.doi.org/10.1186/1471-2202-11-50