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Coaggregation of FcεRI with FcγRIIB Inhibits Degranulation but Not Induction of Bcl-2 Family Members A1 and Bim in Mast Cells

The aggregation of high-affinity immunoglobulin E (IgE) receptors (FcεRI) on mast cells is a critical event in the initiation of an allergic reaction. Coengagement of FcεRI with immunoglobulin G (IgG) low-affinity receptor FcγRIIB/CD32 inhibits degranulation and the release of inflammatory mediators...

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Detalles Bibliográficos
Autores principales: Ekoff, Maria, Möller, Christine, Xiang, Zou, Nilsson, Gunnar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876181/
https://www.ncbi.nlm.nih.gov/pubmed/20525153
http://dx.doi.org/10.1186/1710-1492-2-3-87