Gβ5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling

The type 5 G protein β subunit (Gβ5) can form complexes with members of the Regulator of G protein Signaling 7 (RGS7) family, but the relevance to neuronal G protein signaling is unclear. We report that mouse RGS7/Gβ5 complexes bind to G protein–gated potassium channels and facilitate their function...

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Detalles Bibliográficos
Autores principales: Xie, Keqiang, Allen, Kevin L., Kourrich, Saïd, Colón–Saez, José, Thomas, Mark J., Wickman, Kevin, Martemyanov, Kirill A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876203/
https://www.ncbi.nlm.nih.gov/pubmed/20453851
http://dx.doi.org/10.1038/nn.2549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876203/
https://www.ncbi.nlm.nih.gov/pubmed/20453851
http://dx.doi.org/10.1038/nn.2549

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