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Functional impact of a single nucleotide polymorphism in the OPRD1 promoter region

The δ-opioid receptor mediates rewarding effects of many substances of abuse. We reported an increased frequency of the minor G-allele of single nucleotide polymorphism (SNP) rs569356 [the only variant identified so far in the promoter region of the δ-opioid receptor gene (OPRD1)] in subjects with o...

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Detalles Bibliográficos
Autores principales: Zhang, Huiping, Gelernter, Joel, Gruen, Jeffrey R., Kranzler, Henry R., Herman, Aryeh I., Simen, Arthur A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876206/
https://www.ncbi.nlm.nih.gov/pubmed/20300121
http://dx.doi.org/10.1038/jhg.2010.22