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Recognition of the Ring-Opened State of Proliferating Cell Nuclear Antigen by Replication Factor C Promotes Eukaryotic Clamp-Loading

[Image: see text] Proliferating cell nuclear antigen (PCNA, sliding clamp) is a toroidal-shaped protein that encircles DNA and plays a pivotal role in DNA replication, modification and repair. To perform its vital functions, the clamp has to be opened and resealed at primer−template junctions by a c...

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Detalles Bibliográficos
Autores principales: Tainer, John A., McCammon, J. Andrew, Ivanov, Ivaylo
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876781/
https://www.ncbi.nlm.nih.gov/pubmed/20455582
http://dx.doi.org/10.1021/ja100365x