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Recognition of the Ring-Opened State of Proliferating Cell Nuclear Antigen by Replication Factor C Promotes Eukaryotic Clamp-Loading
[Image: see text] Proliferating cell nuclear antigen (PCNA, sliding clamp) is a toroidal-shaped protein that encircles DNA and plays a pivotal role in DNA replication, modification and repair. To perform its vital functions, the clamp has to be opened and resealed at primer−template junctions by a c...
Autores principales: | Tainer, John A., McCammon, J. Andrew, Ivanov, Ivaylo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876781/ https://www.ncbi.nlm.nih.gov/pubmed/20455582 http://dx.doi.org/10.1021/ja100365x |
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