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Preoperative oral dextromethorphan does not reduce pain or morphine consumption after open cholecystectomy
BACKGROUND: Dextromethorphan, the D-isomer of the codeine analog levorphanol, is a weak, noncompetitive N-Methyl-D-Aspartate (NMDA) receptor antagonist. It has been suggested that NMDA receptor antagonists induce preemptive analgesia when administered before tissue injury occurs, thus decreasing the...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Medknow Publications
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876936/ https://www.ncbi.nlm.nih.gov/pubmed/20532104 http://dx.doi.org/10.4103/1658-354X.57876 |