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Preoperative oral dextromethorphan does not reduce pain or morphine consumption after open cholecystectomy

BACKGROUND: Dextromethorphan, the D-isomer of the codeine analog levorphanol, is a weak, noncompetitive N-Methyl-D-Aspartate (NMDA) receptor antagonist. It has been suggested that NMDA receptor antagonists induce preemptive analgesia when administered before tissue injury occurs, thus decreasing the...

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Detalles Bibliográficos
Autores principales: Mahmoodzadeh, Hossein, Movafegh, Ali, Beigi, Noshin Mosavi
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876936/
https://www.ncbi.nlm.nih.gov/pubmed/20532104
http://dx.doi.org/10.4103/1658-354X.57876