Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe

Nonsense-mediated mRNA decay (NMD) is a translation-linked process that destroys mRNAs with premature translation termination codons (PTCs). In mammalian cells, NMD is also linked to pre-mRNA splicing, usually PTCs trigger strong NMD only when positioned upstream of at least one intron. The exon jun...

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Detalles Bibliográficos
Autores principales: Wen, Jikai, Brogna, Saverio
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876954/
https://www.ncbi.nlm.nih.gov/pubmed/20360683
http://dx.doi.org/10.1038/emboj.2010.48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876954/
https://www.ncbi.nlm.nih.gov/pubmed/20360683
http://dx.doi.org/10.1038/emboj.2010.48

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