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Principles of membrane protein interactions with annular lipids deduced from aquaporin-0 2D crystals

We have previously described the interactions of aquaporin-0 (AQP0) with dimyristoyl phosphatidylcholine (DMPC) lipids. We have now determined the 2.5 Å structure of AQP0 in two-dimensional (2D) crystals formed with Escherichia coli polar lipids (EPLs), which differ from DMPC both in headgroups and...

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Detalles Bibliográficos
Autores principales: Hite, Richard K, Li, Zongli, Walz, Thomas
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876970/
https://www.ncbi.nlm.nih.gov/pubmed/20389283
http://dx.doi.org/10.1038/emboj.2010.68