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The RNA interference pathway affects midgut infection- and escape barriers for Sindbis virus in Aedes aegypti

BACKGROUND: The RNA interference (RNAi) pathway acts as an innate antiviral immune response in Aedes aegypti, modulating arbovirus infection of mosquitoes. Sindbis virus (SINV; family: Togaviridae, genus: Alphavirus) is an arbovirus that infects Ae. aegypti in the laboratory. SINV strain TR339 encou...

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Detalles Bibliográficos
Autores principales: Khoo, Cynthia CH, Piper, Joseph, Sanchez-Vargas, Irma, Olson, Ken E, Franz, Alexander WE
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877022/
https://www.ncbi.nlm.nih.gov/pubmed/20426860
http://dx.doi.org/10.1186/1471-2180-10-130