Large scale analysis of positional effects of single-base mismatches on microarray gene expression data

BACKGROUND: Affymetrix GeneChips utilize 25-mer oligonucleotides probes linked to a silica surface to detect targets in solution. Mismatches due to single nucleotide polymorphisms (SNPs) can affect the hybridization between probes and targets. Previous research has indicated that binding between pro...

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Detalles Bibliográficos
Autores principales: Duan, Fenghai, Pauley, Mark A, Spindel, Eliot R, Zhang, Li, Norgren, Robert B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877042/
https://www.ncbi.nlm.nih.gov/pubmed/20429935
http://dx.doi.org/10.1186/1756-0381-3-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877042/
https://www.ncbi.nlm.nih.gov/pubmed/20429935
http://dx.doi.org/10.1186/1756-0381-3-2

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