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T Cells Specifically Targeted to Amyloid Plaques Enhance Plaque Clearance in a Mouse Model of Alzheimer's Disease

Patients with Alzheimer's disease (AD) exhibit substantial accumulation of amyloid-β (Aβ) plaques in the brain. Here, we examine whether Aβ vaccination can facilitate the migration of T lymphocytes to specifically target Aβ plaques and consequently enhance their removal. Using a new mouse model...

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Detalles Bibliográficos
Autores principales:	Fisher, Yair, Nemirovsky, Anna, Baron, Rona, Monsonego, Alon
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877087/ https://www.ncbi.nlm.nih.gov/pubmed/20520819 http://dx.doi.org/10.1371/journal.pone.0010830

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