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Preferential Amplification of CD8 Effector-T Cells after Transcutaneous Application of an Inactivated Influenza Vaccine: A Randomized Phase I Trial

BACKGROUND: Current conventional vaccination approaches do not induce potent CD8 T-cell responses for fighting mostly variable viral diseases such as influenza, avian influenza viruses or HIV. Following our recent study on vaccine penetration by targeting of vaccine to human hair follicular ducts su...

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Detalles Bibliográficos
Autores principales: Combadière, Behazine, Vogt, Annika, Mahé, Brice, Costagliola, Dominique, Hadam, Sabrina, Bonduelle, Olivia, Sterry, Wolfram, Staszewski, Shlomo, Schaefer, Hans, van der Werf, Sylvie, Katlama, Christine, Autran, Brigitte, Blume-Peytavi, Ulrike
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877091/
https://www.ncbi.nlm.nih.gov/pubmed/20520820
http://dx.doi.org/10.1371/journal.pone.0010818