Responsiveness to PI3K and MEK Inhibitors in Breast Cancer. Use of a 3D Culture System to Study Pathways Related to Hormone Independence in Mice

BACKGROUND: A significant proportion of breast cancer patients face failure of endocrine therapy due to the acquisition of endocrine resistance. We have explored mechanisms involved in such disease progression by using a mouse breast cancer model that is induced by medroxyprogesterone acetate (MPA)....

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Detalles Bibliográficos
Autores principales: Polo, Maria Laura, Arnoni, Maria Victoria, Riggio, Marina, Wargon, Victoria, Lanari, Claudia, Novaro, Virginia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877092/
https://www.ncbi.nlm.nih.gov/pubmed/20520761
http://dx.doi.org/10.1371/journal.pone.0010786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877092/
https://www.ncbi.nlm.nih.gov/pubmed/20520761
http://dx.doi.org/10.1371/journal.pone.0010786

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