Release of Membrane-Bound Vesicles and Inhibition of Tumor Cell Adhesion by the Peptide Neopetrosiamide A

BACKGROUND: Neopetrosiamide A (NeoA) is a 28-amino acid tricyclic peptide originally isolated from a marine sponge as a tumor cell invasion inhibitor whose mechanism of action is unknown. METHODOLOGY/PRINCIPAL FINDINGS: We show that NeoA reversibly inhibits tumor cell adhesion, disassembles focal ad...

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Detalles Bibliográficos
Autores principales: Austin, Pamela, Heller, Markus, Williams, David E., McIntosh, Lawrence P., Vogl, A. Wayne, Foster, Leonard J., Andersen, Raymond J., Roberge, Michel, Roskelley, Calvin D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877099/
https://www.ncbi.nlm.nih.gov/pubmed/20520768
http://dx.doi.org/10.1371/journal.pone.0010836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877099/
https://www.ncbi.nlm.nih.gov/pubmed/20520768
http://dx.doi.org/10.1371/journal.pone.0010836

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