HDAC6 Regulates Mitochondrial Transport in Hippocampal Neurons

BACKGROUND: Tubulin is a major substrate of the cytoplasmic class II histone deacetylase HDAC6. Inhibition of HDAC6 results in higher levels of acetylated tubulin and enhanced binding of the motor protein kinesin-1 to tubulin, which promotes transport of cargoes along microtubules. Microtubule-depen...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Sigeng, Owens, Geoffrey C., Makarenkova, Helen, Edelman, David B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877100/
https://www.ncbi.nlm.nih.gov/pubmed/20520769
http://dx.doi.org/10.1371/journal.pone.0010848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877100/
https://www.ncbi.nlm.nih.gov/pubmed/20520769
http://dx.doi.org/10.1371/journal.pone.0010848

Ejemplares similares