Targeted Mutation of the Mouse Grp94 Gene Disrupts Development and Perturbs Endoplasmic Reticulum Stress Signaling

Glucose-regulated protein 94 (GRP94) is one of the most abundant endoplasmic reticulum (ER) resident proteins and is the ER counterpart of the cytoplasmic heat shock protein 90 (HSP90). GRP94, a component of the GRP78 chaperone system in protein processing, has pro-survival properties with implicate...

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Detalles Bibliográficos
Autores principales: Mao, Changhui, Wang, Miao, Luo, Biquan, Wey, Shiuan, Dong, Dezheng, Wesselschmidt, Robin, Rawlings, Stephen, Lee, Amy S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877114/
https://www.ncbi.nlm.nih.gov/pubmed/20520781
http://dx.doi.org/10.1371/journal.pone.0010852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877114/
https://www.ncbi.nlm.nih.gov/pubmed/20520781
http://dx.doi.org/10.1371/journal.pone.0010852

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