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Effective Dosage and Administration Schedule of Oral Alendronate for Non-nociceptive Symptoms in Rats with Chronic Constriction Injury

We evaluated the efficacy of oral alendronate with different dosing regimens for non-nociceptive symptoms and osteoporosis in a sciatic nerve chronic constriction injury (CCI) model. Male Sprague-Dawley rats (n=60) were subdivided into sham control (SC) group and CCI groups, which were divided accor...

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Detalles Bibliográficos
Autores principales: Im, Sun, Lim, Seong-Hoon, Lee, Jong-In, Ko, Young-Jin, Park, Joo Hyun, Hong, Bo-Young, Park, Geun-Young
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877239/
https://www.ncbi.nlm.nih.gov/pubmed/20514318
http://dx.doi.org/10.3346/jkms.2010.25.6.938