Orm family proteins mediate sphingolipid homeostasis

Despite the essential roles of sphingolipids as both structural components of membranes and critical signalling molecules, we have a limited understanding of how cells sense and regulate their levels. Here we reveal the function in sphingolipid metabolism of the ORM/ORMDL genes, a conserved gene fam...

Descripción completa

Detalles Bibliográficos
Autores principales: Breslow, David K., Collins, Sean R., Bodenmiller, Bernd, Aebersold, Ruedi, Simons, Kai, Shevchenko, Andrej, Ejsing, Christer S., Weissman, Jonathan S.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877384/
https://www.ncbi.nlm.nih.gov/pubmed/20182505
http://dx.doi.org/10.1038/nature08787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877384/
https://www.ncbi.nlm.nih.gov/pubmed/20182505
http://dx.doi.org/10.1038/nature08787

Ejemplares similares