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Trazodone effects on [(3)H]-paroxetine and α(2)-adrenoreceptors in platelets of patients with major depression

Trazodone is an antidepressant which behaves as a selective 5-HT(2) antagonist and 5-HT reuptake inhibitor. The lack of information on its effects in vivo prompted us to evaluate α(2)-adrenoceptors by means of the specific binding of [(3)H]-rauwolscine, and the 5-HT transporter (SERT) by means of th...

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Detalles Bibliográficos
Autores principales: Marazziti, Donatella, Consoli, Giorgio, Golia, Francesca, Baroni, Stefano, Masala, Irene, Carlini, Marina, Dell’Osso, Mario Catena
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877607/
https://www.ncbi.nlm.nih.gov/pubmed/20520789