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Conversion of Adult Pancreatic α-cells to β-cells After Extreme β-cell Loss
Pancreatic insulin-producing β-cells have a long lifespan, such that in healthy conditions they replicate little during a lifetime. Nevertheless, they show increased self-duplication upon increased metabolic demand or after injury (i.e. β-cell loss). It is unknown if adult mammals can differentiate...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877635/ https://www.ncbi.nlm.nih.gov/pubmed/20364121 http://dx.doi.org/10.1038/nature08894 |