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Arf3 Is Activated Uniquely at the trans-Golgi Network by Brefeldin A-inhibited Guanine Nucleotide Exchange Factors

It is widely assumed that class I and II Arfs function interchangeably throughout the Golgi complex. However, we report here that in vivo, Arf3 displays several unexpected properties. Unlike other Golgi-localized Arfs, Arf3 associates selectively with membranes of the trans-Golgi network (TGN) in a...

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Detalles Bibliográficos
Autores principales: Manolea, Florin, Chun, Justin, Chen, David W., Clarke, Ian, Summerfeldt, Nathan, Dacks, Joel B., Melançon, Paul
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877642/
https://www.ncbi.nlm.nih.gov/pubmed/20357002
http://dx.doi.org/10.1091/mbc.E10-01-0016