Essential Role for the CRAC Activation Domain in Store-dependent Oligomerization of STIM1

Oligomerization of the ER Ca(2+) sensor STIM1 is an essential step in store-operated Ca(2+) entry. The lumenal EF-hand and SAM domains of STIM1 are believed to initiate oligomerization after Ca(2+) store depletion, but the contributions of STIM1 cytosolic domains (coiled-coil 1, CC1; coiled-coil 2,...

Descripción completa

Detalles Bibliográficos
Autores principales: Covington, Elizabeth D., Wu, Minnie M., Lewis, Richard S.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877647/
https://www.ncbi.nlm.nih.gov/pubmed/20375143
http://dx.doi.org/10.1091/mbc.E10-02-0145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877647/
https://www.ncbi.nlm.nih.gov/pubmed/20375143
http://dx.doi.org/10.1091/mbc.E10-02-0145

Ejemplares similares