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Essential Role for the CRAC Activation Domain in Store-dependent Oligomerization of STIM1

Oligomerization of the ER Ca(2+) sensor STIM1 is an essential step in store-operated Ca(2+) entry. The lumenal EF-hand and SAM domains of STIM1 are believed to initiate oligomerization after Ca(2+) store depletion, but the contributions of STIM1 cytosolic domains (coiled-coil 1, CC1; coiled-coil 2,...

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Detalles Bibliográficos
Autores principales:	Covington, Elizabeth D., Wu, Minnie M., Lewis, Richard S.
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877647/ https://www.ncbi.nlm.nih.gov/pubmed/20375143 http://dx.doi.org/10.1091/mbc.E10-02-0145

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