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The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy

BACKGROUND: Neoplastic overgrowth depends on the cooperation of several mutations ultimately leading to major rearrangements in cellular behaviour. Precancerous cells are often removed by cell death from normal tissues in the early steps of the tumourigenic process, but the molecules responsible for...

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Detalles Bibliográficos
Autores principales: Froldi, Francesca, Ziosi, Marcello, Garoia, Flavio, Pession, Andrea, Grzeschik, Nicola A, Bellosta, Paola, Strand, Dennis, Richardson, Helena E, Pession, Annalisa, Grifoni, Daniela
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877678/
https://www.ncbi.nlm.nih.gov/pubmed/20374622
http://dx.doi.org/10.1186/1741-7007-8-33