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The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy
BACKGROUND: Neoplastic overgrowth depends on the cooperation of several mutations ultimately leading to major rearrangements in cellular behaviour. Precancerous cells are often removed by cell death from normal tissues in the early steps of the tumourigenic process, but the molecules responsible for...
Autores principales: | Froldi, Francesca, Ziosi, Marcello, Garoia, Flavio, Pession, Andrea, Grzeschik, Nicola A, Bellosta, Paola, Strand, Dennis, Richardson, Helena E, Pession, Annalisa, Grifoni, Daniela |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877678/ https://www.ncbi.nlm.nih.gov/pubmed/20374622 http://dx.doi.org/10.1186/1741-7007-8-33 |
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