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Predictors of natively unfolded proteins: unanimous consensus score to detect a twilight zone between order and disorder in generic datasets

BACKGROUND: Natively unfolded proteins lack a well defined three dimensional structure but have important biological functions, suggesting a re-assignment of the structure-function paradigm. To assess that a given protein is natively unfolded requires laborious experimental investigations, then reli...

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Detalles Bibliográficos
Autores principales: Deiana, Antonio, Giansanti, Andrea
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877690/
https://www.ncbi.nlm.nih.gov/pubmed/20409339
http://dx.doi.org/10.1186/1471-2105-11-198