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Mycobacterium tuberculosis Transcriptional Adaptation, Growth Arrest and Dormancy Phenotype Development Is Triggered by Vitamin C

BACKGROUND: Tubercle bacilli are thought to persist in a dormant state during latent tuberculosis (TB) infection. Although little is known about the host factors that induce and maintain Mycobacterium tuberculosis (M. tb) within latent lesions, O(2) depletion, nutrient limitation and acidification a...

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Detalles Bibliográficos
Autores principales: Taneja, Neetu Kumra, Dhingra, Sakshi, Mittal, Aditya, Naresh, Mohit, Tyagi, Jaya Sivaswami
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877710/
https://www.ncbi.nlm.nih.gov/pubmed/20523728
http://dx.doi.org/10.1371/journal.pone.0010860