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Combination of Pneumococcal Surface Protein A (PspA) with Whole Cell Pertussis Vaccine Increases Protection Against Pneumococcal Challenge in Mice

Streptococcus pneumoniae is the leading cause of respiratory acute infections around the world. In Latin America, approximately 20,000 children under 5 years of age die of pneumococcal diseases annually. Pneumococcal surface protein A (PspA) is among the best-characterized pneumococcal antigens that...

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Detalles Bibliográficos
Autores principales: Oliveira, Maria Leonor S., Miyaji, Eliane N., Ferreira, Daniela M., Moreno, Adriana T., Ferreira, Patricia C. D., Lima, Fernanda A., Santos, Fernanda L., Sakauchi, Maria Aparecida, Takata, Célia S., Higashi, Hisako G., Raw, Isaías, Kubrusly, Flavia S., Ho, Paulo L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877721/
https://www.ncbi.nlm.nih.gov/pubmed/20523738
http://dx.doi.org/10.1371/journal.pone.0010863