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Combination of Pneumococcal Surface Protein A (PspA) with Whole Cell Pertussis Vaccine Increases Protection Against Pneumococcal Challenge in Mice
Streptococcus pneumoniae is the leading cause of respiratory acute infections around the world. In Latin America, approximately 20,000 children under 5 years of age die of pneumococcal diseases annually. Pneumococcal surface protein A (PspA) is among the best-characterized pneumococcal antigens that...
Autores principales: | Oliveira, Maria Leonor S., Miyaji, Eliane N., Ferreira, Daniela M., Moreno, Adriana T., Ferreira, Patricia C. D., Lima, Fernanda A., Santos, Fernanda L., Sakauchi, Maria Aparecida, Takata, Célia S., Higashi, Hisako G., Raw, Isaías, Kubrusly, Flavia S., Ho, Paulo L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877721/ https://www.ncbi.nlm.nih.gov/pubmed/20523738 http://dx.doi.org/10.1371/journal.pone.0010863 |
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