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Manipulation of Behavioral Decline in Caenorhabditis elegans with the Rag GTPase raga-1

Normal aging leads to an inexorable decline in motor performance, contributing to medical morbidity and decreased quality of life. While much has been discovered about genetic determinants of lifespan, less is known about modifiers of age-related behavioral decline and whether new gene targets may b...

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Detalles Bibliográficos
Autores principales: Schreiber, Matthew A., Pierce-Shimomura, Jonathan T., Chan, Stefan, Parry, Dianne, McIntire, Steven L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877737/
https://www.ncbi.nlm.nih.gov/pubmed/20523893
http://dx.doi.org/10.1371/journal.pgen.1000972