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Sgs1 and Exo1 Redundantly Inhibit Break-Induced Replication and De Novo Telomere Addition at Broken Chromosome Ends

In budding yeast, an HO endonuclease-inducible double-strand break (DSB) is efficiently repaired by several homologous recombination (HR) pathways. In contrast to gene conversion (GC), where both ends of the DSB can recombine with the same template, break-induced replication (BIR) occurs when only t...

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Detalles Bibliográficos
Autores principales: Lydeard, John R., Lipkin-Moore, Zachary, Jain, Suvi, Eapen, Vinay V., Haber, James E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877739/
https://www.ncbi.nlm.nih.gov/pubmed/20523895
http://dx.doi.org/10.1371/journal.pgen.1000973