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Sgs1 and Exo1 Redundantly Inhibit Break-Induced Replication and De Novo Telomere Addition at Broken Chromosome Ends
In budding yeast, an HO endonuclease-inducible double-strand break (DSB) is efficiently repaired by several homologous recombination (HR) pathways. In contrast to gene conversion (GC), where both ends of the DSB can recombine with the same template, break-induced replication (BIR) occurs when only t...
Autores principales: | Lydeard, John R., Lipkin-Moore, Zachary, Jain, Suvi, Eapen, Vinay V., Haber, James E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877739/ https://www.ncbi.nlm.nih.gov/pubmed/20523895 http://dx.doi.org/10.1371/journal.pgen.1000973 |
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