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Epistasis of Transcriptomes Reveals Synergism between Transcriptional Activators Hnf1α and Hnf4α

The transcription of individual genes is determined by combinatorial interactions between DNA–binding transcription factors. The current challenge is to understand how such combinatorial interactions regulate broad genetic programs that underlie cellular functions and disease. The transcription fact...

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Detalles Bibliográficos
Autores principales: Boj, Sylvia F., Petrov, Dimitri, Ferrer, Jorge
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877749/
https://www.ncbi.nlm.nih.gov/pubmed/20523905
http://dx.doi.org/10.1371/journal.pgen.1000970