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Aging and Chronic Sun Exposure Cause Distinct Epigenetic Changes in Human Skin
Epigenetic changes are widely considered to play an important role in aging, but experimental evidence to support this hypothesis has been scarce. We have used array-based analysis to determine genome-scale DNA methylation patterns from human skin samples and to investigate the effects of aging, chr...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877750/ https://www.ncbi.nlm.nih.gov/pubmed/20523906 http://dx.doi.org/10.1371/journal.pgen.1000971 |