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Aging and Chronic Sun Exposure Cause Distinct Epigenetic Changes in Human Skin

Epigenetic changes are widely considered to play an important role in aging, but experimental evidence to support this hypothesis has been scarce. We have used array-based analysis to determine genome-scale DNA methylation patterns from human skin samples and to investigate the effects of aging, chr...

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Detalles Bibliográficos
Autores principales: Grönniger, Elke, Weber, Barbara, Heil, Oliver, Peters, Nils, Stäb, Franz, Wenck, Horst, Korn, Bernhard, Winnefeld, Marc, Lyko, Frank
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877750/
https://www.ncbi.nlm.nih.gov/pubmed/20523906
http://dx.doi.org/10.1371/journal.pgen.1000971