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Genetic variation within the gene encoding the HIV-1 CCR5 coreceptor in two South African populations

Polymorphisms within the open reading frame as well as the promoter and regulatory regions can influence the amount of CCR5 expressed on the cell surface and hence an individual's susceptibility to HIV-1. In this study we characterize CCR5 genes within the South African African (SAA) and Caucas...

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Detalles Bibliográficos
Autores principales: Picton, Anabela C.P., Paximadis, Maria, Tiemessen, Caroline T.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877777/
https://www.ncbi.nlm.nih.gov/pubmed/20206716
http://dx.doi.org/10.1016/j.meegid.2010.02.012