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Stimulation of TRPC5 cationic channels by low micromolar concentrations of lead ions (Pb(2+))

Lead toxicity is long-recognised but continues to be a major public health problem. Its effects are wide-ranging and include induction of hyper-anxiety states. In general it is thought to act by interfering with Ca(2+) signalling but specific targets are not clearly identified. Transient receptor po...

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Detalles Bibliográficos
Autores principales: Sukumar, Piruthivi, Beech, David J.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877782/
https://www.ncbi.nlm.nih.gov/pubmed/20100462
http://dx.doi.org/10.1016/j.bbrc.2010.01.074