Structural and Functional Analysis of the Engineered Type I DNA Methyltransferase EcoR124I(NT)

The Type I R–M system EcoR124I is encoded by three genes. HsdM is responsible for modification (DNA methylation), HsdS for DNA sequence specificity and HsdR for restriction endonuclease activity. The trimeric methyltransferase (M(2)S) recognises the asymmetric sequence (GAAN(6)RTCG). An engineered R...

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Detalles Bibliográficos
Autores principales: Taylor, James E.N., Callow, Phil, Swiderska, Anna, Kneale, G. Geoff
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877798/
https://www.ncbi.nlm.nih.gov/pubmed/20302878
http://dx.doi.org/10.1016/j.jmb.2010.03.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877798/
https://www.ncbi.nlm.nih.gov/pubmed/20302878
http://dx.doi.org/10.1016/j.jmb.2010.03.008

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