Thermodynamics of RTA3 peptide binding to membranes and consequences for antimicrobial activity()

RTA3 is an α-helical, amphipathic peptide with broad-spectrum activity against Gram-negative bacteria and low mammalian cell toxicity. RTA3 contains a cysteine residue, replacement of which with an alanine or serine (RTA3-C15S) virtually abolishes antimicrobial activity. Much of the activity of RTA3...

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Detalles Bibliográficos
Autores principales: Hawrani, Ayman, Howe, Robin A., Walsh, Timothy R., Dempsey, Christopher E.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877818/
https://www.ncbi.nlm.nih.gov/pubmed/20346912
http://dx.doi.org/10.1016/j.bbamem.2010.03.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877818/
https://www.ncbi.nlm.nih.gov/pubmed/20346912
http://dx.doi.org/10.1016/j.bbamem.2010.03.017

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