Merotelic attachments and non-homologous end joining are the basis of chromosomal instability

Although the large majority of solid tumors show a combination of mitotic spindle defects and chromosomal instability, little is known about the mechanisms that govern the initial steps in tumorigenesis. The recent report of spindle-induced DNA damage provides evidence for a single mechanism respons...

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Detalles Bibliográficos
Autores principales: Guerrero, Astrid Alonso, Martínez-A, Carlos, van Wely, Karel HM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878296/
https://www.ncbi.nlm.nih.gov/pubmed/20478024
http://dx.doi.org/10.1186/1747-1028-5-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878296/
https://www.ncbi.nlm.nih.gov/pubmed/20478024
http://dx.doi.org/10.1186/1747-1028-5-13

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