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Multiple Phosphatidylinositol 3-Kinases Regulate Vaccinia Virus Morphogenesis

Poxvirus morphogenesis is a complex process that involves the successive wrapping of the virus in host cell membranes. We screened by plaque assay a focused library of kinase inhibitors for those that caused a reduction in viral growth and identified several compounds that selectively inhibit phosph...

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Detalles Bibliográficos
Autores principales: McNulty, Shannon, Bornmann, William, Schriewer, Jill, Werner, Chas, Smith, Scott K., Olson, Victoria A., Damon, Inger K., Buller, R. Mark, Heuser, John, Kalman, Daniel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878334/
https://www.ncbi.nlm.nih.gov/pubmed/20526370
http://dx.doi.org/10.1371/journal.pone.0010884