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Dynamics of Lamin-A Processing Following Precursor Accumulation

Lamin A (LaA) is a component of the nuclear lamina, an intermediate filament meshwork that underlies the inner nuclear membrane (INM) of the nuclear envelope (NE). Newly synthesized prelamin A (PreA) undergoes extensive processing involving C-terminal farnesylation followed by proteolysis yielding n...

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Detalles Bibliográficos
Autores principales: Liu, Qian, Kim, Dae In, Syme, Janet, LuValle, Phyllis, Burke, Brian, Roux, Kyle J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878336/
https://www.ncbi.nlm.nih.gov/pubmed/20526372
http://dx.doi.org/10.1371/journal.pone.0010874