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Dynamics of Lamin-A Processing Following Precursor Accumulation
Lamin A (LaA) is a component of the nuclear lamina, an intermediate filament meshwork that underlies the inner nuclear membrane (INM) of the nuclear envelope (NE). Newly synthesized prelamin A (PreA) undergoes extensive processing involving C-terminal farnesylation followed by proteolysis yielding n...
Autores principales: | Liu, Qian, Kim, Dae In, Syme, Janet, LuValle, Phyllis, Burke, Brian, Roux, Kyle J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878336/ https://www.ncbi.nlm.nih.gov/pubmed/20526372 http://dx.doi.org/10.1371/journal.pone.0010874 |
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